A global approach to the teaching and learning of Yoruba as a second language (L2) can be used to understand the language processes that underlie societal change and the development resulting from a world of increasing interconnections and interactions. Yoruba language plays two different roles in education. It is used for instruction as a subject and it is used as a media of instruction generally. The National Policy on Education (1977, Revised 1981,1989,1998) recognizes the multilingual situation in Nigeria by encouraging the teaching and learning of Yoruba as a second language (L2). This paper examines the effects of globalization on the teaching and learning of Yoruba as a second language by examining critically the problems and the prospects of this language in the Colleges of Education in Nigeria.